NMN and Weight loss?

A new study published recently showed that NMN supplementation increases the activity of metabolism-related genes and diminishes inflammation and scarring-related gene activity in fat cells.

Obesity is correlated with conditions such as diabetes, high blood pressure and heart disease.

Hence, if translatable to people, taking NMN may prevent obesity-related diseases by improving gene activity related to metabolism and reduction of inflammation.

Some studies have shown that NAD+ is in lower levels in obese people.

By taking NMN, NAD+ in our bodies is boosted to a higher level, helping to maintain metabolism and DNA repair.

NMN also increased gene activity for an “appetite-suppressant” hormone molecule called leptin.

This seems to suggest that perhaps, NMN supplementation may even aid people in their weight loss journeys.

Reference

Majeed Y, Halabi N, Madani A, Engelke R, Bhagwat A, Abdesselem H et al. SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways. Scientific Reports. 2021;11(1).