NMN helps to improve Blood Glucose Control, potential to reverse prediabetes

A benefit of taking NMN is that it increases insulin sensitivity, helping to delay the progression of prediabetes to diabetes, or even reversing it. This effect of NMN is demonstrated in an article published on Science.org about the effect of NMN on prediabetic patients. An article was published on 11 June 2021 by Yoshino et al, titled “Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women”. In this study, a 10 week, randomised, placebo-controlled, double-blind trial was conducted. This kind of study is often considered the most reliable and highest standard possible for research studies.

Subjects of this trial were 25 postmenopausal women with prediabetes who were overweight or obese. Prediabetes is the stage right before diabetes has fully developed. In more technical terms, prediabetes is when a person has a HbA1C reading between 5.7-6.4%. This means that the patient’s blood sugar has been slightly elevated for the past 3 months. The key thing about prediabetes is that it is still reversible, and one might not develop diabetes.

Results of this research has shown that among those subjects who had taken NMN, there was upregulation of muscle remodelling genes and platelet derived growth factors. This indicates that muscles were remodelled to increase muscle insulin sensitivity, insulin signalling, thus helping to decrease blood glucose levels and HbA1C levels. As blood glucose levels and HbA1C levels decrease, progression of prediabetes can be delayed or even reversed.

Taking NMN can help to improve insulin sensitivity and blood glucose control in everyone, not only those with prediabetes.

Full article link below

https://www.science.org/doi/10.1126/science.abe9985#body-ref-R12-1