NMN Limits Liver Damage with Alcohol Consumption in Mice

It is common knowledge that chronic alcohol consumption can result in liver damage, and in the long term liver failure. In some cases of liver cirrhosis, liver cancer may also develop.

A team of researchers recently identified how nicotinamide mononucleotide (NMN) supplementation can make a difference in liver damage from chronic alcohol consumption.

Liver damage is measured by liver enzyme markers AST and ALT which would be elevated in patients with liver damage.

In the study done, supplementing NMN helped to reduce and limit liver damage in mice with alcohol consumption.

In this case, NMN may prove to be of benefit as a supplement to patients with chronic alcohol consumption, or who have liver damage.

Reference : Assiri MA, Ali HR, Marentette JO, Yun Y, Liu J, Hirschey MD, Saba LM, Harris PS, Fritz KS. Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease. Hum Genomics. 2019 Dec 10;13(1):65. doi: 10.1186/s40246-019-0251-1. PMID: 31823815; PMCID: PMC6902345.